For those who want the quick version, the video explainer is at the bottom of this post. There are a multitude of things that are worth predicting about DNA and a multitude of ways to predict them. Starting with the ways of predicting properties of DNA, there are unsupervised methods like BLAST (sequence alignment) where …
June 2022
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Predicting Drug Toxicity With Chemi-Informatics and Machine Learning
For those who want the quick version, the video explainer is at the bottom of this post. The ability to predict a specific property or outcome of a chemical and/or its interaction with a system is nothing new to those familiar with quantitative structure-activity relationship (QSAR) modelin. I picked toxicity as the property to predict …
From Pairwise to Batch Sequence Alignment in R
Alignment. What Is It Good For? One of the most common and important bioinformatic analyses is the aligning biological sequences like DNA, RNA, and protein against other similar sequences. These alignments can ranges from pairwise (one sequence vs another sequence) to multi-sequence alignment (many sequences vs many sequences). The alignment can be used to calculate …